Med Cutan.Ibero.Lat.Am 1986;14(2):133-137. View abstract. According to the same source, EPO may cause labor abnormalities. Inflamm.Bowel.Dis 2002;8(3):174-179. Arzneimittelforschung 2007;57(9):607-615. Br J Psychiatry 1999;175:88. Centre for Reviews and Dissemination. J R.Soc Med 1992;85(1):12-15. J Med Food 2007;10(4):662-6. Am J Obstet Gynecol. J Fam.Pract. Prostaglandins Med 1981;6(4):375-379. When taken in appropriate amounts short term, oral use of evening primrose oil is most likely safe.Evening primrose oil can cause: 1. Ferrando, J. Effect of oral gamolenic acid from evening primrose oil on menopausal flushing (abstract). and Lipids. The effects of vitamin D and evening primrose oil co-supplementation on lipid profiles and biomarkers of oxidative stress in vitamin D-deficient women with polycystic ovary syndrome: a randomized double-blind, placebo-controlled trial. View abstract. View abstract. Scand.J Rheumatol.Suppl 1986;61:242-245. Greaves, M. W. and Corbett, M. F. Treatment of atopic eczema with evening primrose oil. Proc.2nd International Symposium on Premenstrual, Postpartum and Menopausal Mood Disorders 1987;abstract 44. A., Roelfsema, H., Zecevic, J., Graham, T. E., and Holub, B. J. Evening primrose hypertension hope. View abstract. Reduction of 5-azacitidine induced skin reactions in MDS patients with evening primrose oil. Aust N Z J Surg 1999;69:492-4.. View abstract. View abstract. Rhinology 2011;49(3):342-346. Wong, A. H., Smith, M., and Boon, H. S. Herbal remedies in psychiatric practice. Dove D, Johnson P. Oral evening primrose oil: its effect on length of pregnancy and selected intrapartum outcomes in low-risk nulliparous women (abstract). View abstract. 1991;14(9):282. Disorders affecting bile flow in the liver. View abstract. J.Atten.Disord. View abstract. Lancet 5-26-1990;335(8700):1283. View abstract. Warnings. Clinical benefits of n-3 PUFA and gamma-Linolenic acid in patients with rheumatoid arthritis. These medications are commonly prescribed to those suffering from depression. Early research shows that taking 4.8 grams of evening primrose per day for 12 weeks does not add to the weight loss achieved with a reduced calorie diet in obese women. BMJ 2003;327:1385. Barabino, S., Rolando, M., Camicione, P., Ravera, G., Zanardi, S., Giuffrida, S., and Calabria, G. Systemic linoleic and gamma-linolenic acid therapy in dry eye syndrome with an inflammatory component. 1981;3(2):118-139. View abstract. Taking evening primrose oil with phenothiazines might increase the risk of having a seizure in some people. Evening primrose oil might interact with medications used during surgery. Fortschritte der Medizin 1991;109(19):11. View abstract. Effect of primrose oil on serum lipids and blood pressure in hyperlipidemic subjects. 1990;586:288-294. 2020;27(2):194-198. Kruger, M. C., Coetzer, H., de Winter, R., Gericke, G., and van Papendorp, D. H. Calcium, gamma-linolenic acid and eicosapentaenoic acid supplementation in senile osteoporosis. View abstract. Lancet 1993;341:1557-60. Labruzzo, B. Laugharne, J. D., Mellor, J. E., and Peet, M. Fatty acids and schizophrenia. Effect of a compound containing isoflavones, primrose oil and vitamin E in two different doses on climacteric symptoms. Prostaglandins Leukot Essent Fatty Acids 1994;51:311-6. LIVESTRONG is a registered trademark of the LIVESTRONG Foundation. View abstract. 2020;34(10):2628-2638. Painful response to cold especially in the fingers and toes (Raynaud syndrome). Prostaglandins Leukot Essent Fatty Acids 1989;37(3):145-147. View abstract. View abstract. J Obstet Gynaecol 2006;26(4):344-347. Complementary/alternative therapies for premenstrual syndrome: a systematic review of randomized controlled trials (Structured abstract). View abstract. Most of the time it happens because the dose is too high. She owns ShapeYourEnergy, a popular health and fitness website. Lack of effect of evening primrose oil on autonomic function tests after 12 months of treatment. Jones, L. Essential Fatty Acids and Dry Eye: What Do We Know? Strong A and Hamill E. The effect of combined fish oil and evening primrose oil (Efamol Marine) on the remission phase of psoriasis: a 7-month double-blind randomized placebo-controlled trial. View abstract. Med Hypotheses 1979;5(3):365-378. View abstract. Lets take a look at other precautions to be mindful of when using evening primrose oil. Saied GM, Kamel RM, and Dessouki N. Low intensity laser therapy is comparable to bromocriptine-evening primrose oil for the treatment of cyclical mastalgia in Egyptian females. Nutr Cancer 1995;24:33-45. . Effects of linoleic acid and gamma-linolenic acid on the growth and metastasis of a human breast cancer cell line in nude mice and on its growth and invasive capacity in vitro. View abstract. 1993;27(12):1475-1477. © 2005 - 2019 WebMD LLC. Kelley, K. W. and Carroll, D. G. Evaluating the evidence for over-the-counter alternatives for relief of hot flashes in menopausal women. Int J Cancer 2000;85:643-8. Cancer Lett. Evening primrose oil (Efamol) in the treatment of children with atopic eczema. Horrobin, D. F. Effects of evening primrose oil in rheumatoid arthritis. View abstract. advertisements are served by third party advertising companies. Can Fam.Physician 2002;48:1789-1797. . Jantti, J., Nikkari, T., Solakivi, T., Vapaatalo, H., and Isomaki, H. Evening primrose oil in rheumatoid arthritis: changes in serum lipids and fatty acids. 2011;(12):CD000376. Side Effects of Evening Primrose Oil for Menopause. View abstract. View abstract. Therapeutic effects of precursors in the form of evening primrose oil (Oenothera)]. The risks are even greater for pregnant women who use this remedy to reduce labor time. Current research contradicts anecdotal evidence. Haimov-Kochman, R. and Hochner-Celnikier, D. Hot flashes revisited: pharmacological and herbal options for hot flashes management. Anstey A, Quigley M, Wilkinson JD. Prevention of nerve conduction deficit in diabetic rats by polyunsaturated fatty acids. Head RJ, McLennan PL, Raederstorff D, et al. Evening primrose is LIKELY SAFE for most people when used in doses up to 6 grams daily for up to a year. Ann.Rheum.Dis 1989;48(2):124-127. Sharif SN, Darsareh F. Impact of evening primrose oil consumption on psychological symptoms of postmenopausal women: a randomized double-blinded placebo-controlled clinical trial. Journal of Dermatological Treatment 1993;4:33-36. Prostagland Leukotrienes Med 1982;8:273-285. View abstract. Diazepam, Levetiracetam, Clonazepam and Topiramate are just a few examples. Seizures! Because evening primrose oil may cause uterine contractions, it is not recommended for pregnant women. (check all that apply), What factors are most important to you? Massil H, Brush M, Manku M, and et al. Evening primrose oil in patients with rheumatoid arthritis and side- effects of non-steroidal anti-inflammatory drugs. Preece PE, Hanslip JI Gilbert L. Evening primrose oil (Efamol) for mastalgia. Lancet 4-7-1990;335(8693):864-865. View abstract. View abstract. Garcia C, Carter J, and Chou A. Gamma linolenic acid causes weight loss and lower blood pressure in overweight patients with family history of obesity. (check all that apply). Horrobin, D. F. and Stewart, C. Evening primrose oil and atopic eczema. Poisson J, Germain-Bellenger S, Engler M, and et al. Holist.Nurs.Pract. Prog Lipid Res 1992;31(2):163-194. Atherosclerosis 1990;81:199-208. View abstract. Lis-Balchin, M. Parallel placebo-controlled clinical study of a mixture of herbs sold as a remedy for cellulite. Central 1989;35. Humphreys F, Symons J, Brown H, and et al. View abstract. Br J Dermatol 2004;150:728-40. This medication contains evening primrose oil. Joint swelling (inflammation) in people with psoriasis. Breast 2007;16(5):503-512. Br J Surg. J Am Diet Assoc 2000;100:1368-80. Huntley, A. L. and Ernst, E. A systematic review of herbal medicinal products for the treatment of menopausal symptoms. View abstract. View abstract. Upset stomach 2. Side Effects What are the side effects of Evening Primrose (Evening Primrose Oil)?. , see natural medicines Comprehensive side effects of evening primrose oil services as well as nutrition counseling Vapaatalo... W., Dettke, T. E., and safety 38 ( 9 ):1482-1499 and during their periods premenstrual! Milosevic, I. G., Safranek, S. Sarwar G. Ali M. Channa G. A. versus. On climacteric symptoms as abdominal pain, fullness, or nausea, Battistutta D. evening oil... In normal subjects ; modulatory roles of evening primrose oil / Tocotrienol is used for short.! Developments in the management of cyclical mastalgia in oriental women: pioneer of! 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